Hypoxia-induced cancer stemness acquisition is associated with CXCR4 activation by its aberrant promoter demethylation

BACKGROUND: A hypoxic microenvironment leads to an increase in the invasiveness and the metastatic potential of cancer cells within tumors via the epithelial-mesenchymal transition (EMT) and cancer stemness acquisition. However, hypoxia-induced changes in the expression and function of candidate ste...

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Detalles Bibliográficos
Publicado en:BMC Cancer
Main Authors: Kang, Nahyeon, Choi, Su Yeon, Kim, Bit Na, Yeo, Chang Dong, Park, Chan Kwon, Kim, Young Kyoon, Kim, Tae-Jung, Lee, Seong-Beom, Lee, Sug Hyung, Park, Jong Y., Park, Mi Sun, Yim, Hyeon Woo, Kim, Seung Joon
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375212/
https://ncbi.nlm.nih.gov/pubmed/30760238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5360-7
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