DNA Damage Response and Repair Gene Alterations Are Associated With Improved Survival In Patients With Platinum-Treated Advanced Urothelial Carcinoma

PURPOSE: Platinum-based chemotherapy remains the standard treatment for advanced urothelial carcinoma by inducing DNA damage. We hypothesize that somatic alterations in DNA damage response and repair (DDR) genes are associated with improved sensitivity to platinum-based chemotherapy. EXPERIMENTAL DE...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Teo, Min Yuen, Bambury, Richard M., Zabor, Emily C., Jordan, Emmet, Al-Ahmadie, Hikmat, Boyd, Mariel E., Bouvier, Nancy, Mullane, Stephanie A., Cha, Eugene K., Roper, Nitin, Ostrovnaya, Irina, Hyman, David M., Bochner, Bernard H., Arcila, Maria E., Solit, David B., Berger, Michael F., Bajorin, Dean F., Bellmunt, Joaquim, Iyer, Gopakumar, Rosenberg, Jonathan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511570/
https://ncbi.nlm.nih.gov/pubmed/28137924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2520
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados