Natural history, response to systemic therapy, and genomic landscape of plasmacytoid urothelial carcinoma

BACKGROUND: Plasmacytoid urothelial carcinoma (PUC) is a rare, aggressive histologic variant of urothelial cancer characterised by a diffuse growth pattern and CDH1 mutation. We studied the efficacy of preoperative platinum-based chemotherapy in nonmetastatic PUC and immune checkpoint inhibitors (IC...

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Опубликовано в: :Br J Cancer
Главные авторы: Teo, Min Yuen, Al-Ahmadie, Hikmat, Seier, Kenneth, Tully, Christopher, Regazzi, Ashley M., Pietzak, Eugene, Solit, David B., Tickoo, Satish, Reuter, Victor, Cha, Eugene K., Herr, Harry, Donahue, Timothy, Donat, Sherri M., Dalbagni, Guido, Bochner, Bernard H., Funt, Samuel, Iyer, Gopakumar V., Bajorin, Dean F., Ostrovnaya, Irina, Rosenberg, Jonathan E.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007750/
https://ncbi.nlm.nih.gov/pubmed/33473164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01244-2
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