Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene

BACKGROUND: Substance P (SP) is a pain- and inflammation-related neuropeptide which preferentially binds to the neurokinin receptor 1 (NK(1)). SP and NK(1) receptors have been implicated in joint pain, inflammation and damage in animal models and human studies of osteoarthritis (OA). The aim of this...

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Detaylı Bibliyografya
Yayımlandı:Eur J Pain
Asıl Yazarlar: Warner, Sophie C, Walsh, David A, Laslett, Laura L, Maciewicz, Rose A, Soni, Anushka, Hart, Deborah J, Zhang, Weiya, Muir, Kenneth R, Dennison, Elaine M, Leaverton, Paul, Rampersaud, Evadnie, Cooper, Cyrus, Spector, Tim D, Cicuttini, Flavia M, Arden, Nigel K, Jones, Graeme, Doherty, Michael, Valdes, Ana M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511507/
https://ncbi.nlm.nih.gov/pubmed/28493529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejp.1027
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