Genetic contribution to radiographic severity in osteoarthritis of the knee

OBJECTIVE: Knee osteoarthritis (OA) has a significant genetic component. The authors have assessed the role of three variants reported to influence risk of knee OA with p<5×10–8 in determining patellofemoral and tibiofemoral Kellgren Lawrence (K/L) grade in knee OA cases. METHODS: 3474 knee OA ca...

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Главные авторы: Valdes, Ana M, Doherty, Sally, Muir, Kenneth R, Zhang, Weiya, Maciewicz, Rose A, Wheeler, Margaret, Arden, Nigel, Cooper, Cyrus, Doherty, M
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Group 2012
Предметы:
Clinical and Epidemiological Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414227/
https://ncbi.nlm.nih.gov/pubmed/22615457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2012-201382
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