An Alpha7 Nicotinic Acetylcholine Receptor Agonist (GTS-21) Promotes C(2)C(12) Myonuclear Accretion in Association with Release of Interleukin-6 (IL-6) and Improves Survival in Burned Mice

The role of interleukin-6 (IL-6) in physiological processes and disease is poorly understood. The hypothesis tested in this study was that selective alpha7 acetylcholine receptor (α7AChR) agonist, GTS-21, releases of IL-6 in association with myonuclear accretion and enhances insulin signaling in mus...

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Publicat a:Shock
Autors principals: Khan, Mohammed A. S., Khan, Mohammed F., Kashiwagi, Shizuka, Kem, William R., Yasuhara, Shingo, Kaneki, Masao, Tompkins, Ronald G., Jeevendra Martyn, J A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511057/
https://ncbi.nlm.nih.gov/pubmed/28282360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000849
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