Prevention of Burn-induced Inflammatory Responses and Muscle Wasting by GTS-21, a Specific Agonist for α7 Nicotinic Acetylcholine Receptors

INTRODUCTION: Muscle wasting (MW) in catabolic conditions (e.g. burn injury, BI) is a major risk factor affecting prognosis. Activation of IL-1β/NF-κB, IL-6/STAT3 and/or FoxO-mediated gene transcription pathways is the pivotal trigger of inflammatory response-induced protein catabolic processes in m...

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Bibliografske podrobnosti
izdano v:Shock
Main Authors: Kashiwagi, Shizuka, Khan, Mohammed A. S., Yasuhara, Shingo, Goto, Takahisa, Tompkins, Ronald G., Kaneki, Masao, Martyn, J. A. Jeevendra
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167674/
https://ncbi.nlm.nih.gov/pubmed/27529131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000729
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