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Alternative lengthening of telomeres and ATRX/DAXX loss can reliably be detected in fine needle aspirates of pancreatic neuroendocrine tumors
PURPOSE: Pancreatic neuroendocrine tumors (PanNETs) frequently utilize the Alternative Lengthening of Telomeres (ALT) pathway for telomere maintenance. ALT is strongly correlated with ATRX and DAXX alterations and a poor prognosis in primary PanNETs. Since fine needle aspiration (FNA) is a non-invas...
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| Pubblicato in: | Cancer |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5511056/ https://ncbi.nlm.nih.gov/pubmed/28371511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncy.21857 |
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