Alternative Lengthening of Telomeres and Loss of DAXX/ATRX Expression Predicts Metastatic Disease and Poor Survival in Patients with Pancreatic Neuroendocrine Tumors

PURPOSE: Pancreatic neuroendocrine tumors (PanNET) are a heterogeneous group of neoplasms with increasing incidence and unpredictable behavior. Whole-exome sequencing has identified recurrent mutations in the genes DAXX and ATRX, which correlate with loss of protein expression and alternative length...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Singhi, Aatur D., Liu, Ta-Chiang, Roncaioli, Justin L., Cao, Dengfeng, Zeh, Herbert J., Zureikat, Amer H., Tsung, Allan, Marsh, J. Wallis, Lee, Kenneth K., Hogg, Melissa E., Bahary, Nathan, Brand, Randall E., McGrath, Kevin M., Slivka, Adam, Cressman, Kristi L., Fuhrer, Kimberly, O’Sullivan, Roderick J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560642/
https://ncbi.nlm.nih.gov/pubmed/27407094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1113
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados