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Circulating soluble P-selectin must dimerize to promote inflammation and coagulation in mice
Leukocyte adhesion to P-selectin on activated platelets and endothelial cells induces shedding of the P-selectin ectodomain into the circulation. Plasma soluble P-selectin (sP-selectin) is elevated threefold to fourfold in patients with cardiovascular disease. Circulating sP-selectin is thought to t...
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| Gepubliceerd in: | Blood |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Hematology
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5510792/ https://ncbi.nlm.nih.gov/pubmed/28515093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-02-770479 |
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