A carregar...
Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force
Selectin interactions with fucosylated glycan ligands mediate leukocyte rolling in the vasculature under shear forces. Crystal structures of P- and E-selectin suggest a two-state model in which ligand binding to the lectin domain closes loop 83–89 around the Ca(2+) coordination site, enabling Glu-88...
Na minha lista:
| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5313117/ https://ncbi.nlm.nih.gov/pubmed/28011641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.767186 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|