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Neutrophils lacking ERM proteins polarize and crawl directionally but have decreased adhesion strength

Ezrin/radixin/moesin (ERM) proteins are adaptors that link the actin cytoskeleton to the cytoplasmic domains of membrane proteins. Leukocytes express mostly moesin with lower levels of ezrin but no radixin. When leukocytes are activated, ERMs are postulated to redistribute membrane proteins from mic...

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Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Panicker, Sumith R., Yago, Tadayuki, Shao, Bojing, McEver, Rodger P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422121/
https://ncbi.nlm.nih.gov/pubmed/32761234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002423
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