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Neutrophils lacking ERM proteins polarize and crawl directionally but have decreased adhesion strength

Ezrin/radixin/moesin (ERM) proteins are adaptors that link the actin cytoskeleton to the cytoplasmic domains of membrane proteins. Leukocytes express mostly moesin with lower levels of ezrin but no radixin. When leukocytes are activated, ERMs are postulated to redistribute membrane proteins from mic...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Panicker, Sumith R., Yago, Tadayuki, Shao, Bojing, McEver, Rodger P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422121/
https://ncbi.nlm.nih.gov/pubmed/32761234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002423
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