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Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5

High-affinity antibody production through the germinal centre (GC) response is a pivotal process in adaptive immunity. Abnormal development of follicular helper T (T(FH)) cells can induce the GC response to self-antigens, subsequently leading to autoimmunity. Here we show the transcriptional repress...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Park, Sungjun, Lee, Seungwon, Lee, Choong-Gu, Park, Guk Yeol, Hong, Hyebeen, Lee, Jeon-Soo, Kim, Young Min, Lee, Sung Bae, Hwang, Daehee, Choi, Youn Soo, Fryer, John D., Im, Sin-Hyeog, Lee, Seung-Woo, Lee, Yoontae
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510180/
https://ncbi.nlm.nih.gov/pubmed/28855737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms16037
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