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Deletion Timing of Cic Alleles during Hematopoiesis Determines the Degree of Peripheral CD4(+) T Cell Activation and Proliferation
Capicua (CIC) is a transcriptional repressor that regulates several developmental processes. CIC deficiency results in lymphoproliferative autoimmunity accompanied by expansion of CD44(hi)CD62L(lo) effector/memory and follicular Th cell populations. Deletion of Cic alleles in hematopoietic stem cell...
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| 出版年: | Immune Netw |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Korean Association of Immunologists
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7609164/ https://ncbi.nlm.nih.gov/pubmed/33163251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2020.20.e43 |
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