Deletion Timing of Cic Alleles during Hematopoiesis Determines the Degree of Peripheral CD4(+) T Cell Activation and Proliferation

Capicua (CIC) is a transcriptional repressor that regulates several developmental processes. CIC deficiency results in lymphoproliferative autoimmunity accompanied by expansion of CD44(hi)CD62L(lo) effector/memory and follicular Th cell populations. Deletion of Cic alleles in hematopoietic stem cell...

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Detalhes bibliográficos
Publicado no:Immune Netw
Main Authors: Park, Guk-Yeol, Lee, Gil-Woo, Kim, Soeun, Hong, Hyebeen, Park, Jong Seok, Cho, Jae-Ho, Lee, Yoontae
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Association of Immunologists 2020
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609164/
https://ncbi.nlm.nih.gov/pubmed/33163251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2020.20.e43
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