Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington’s disease

Huntington’s disease is characterized by a complex and heterogeneous pathogenic profile. Studies have shown that disturbance in lipid homeostasis may represent a critical determinant in the progression of several neurodegenerative disorders. The recognition of perturbed lipid metabolism is only rece...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Di Pardo, Alba, Amico, Enrico, Basit, Abdul, Armirotti, Andrea, Joshi, Piyush, Neely, M. Diana, Vuono, Romina, Castaldo, Salvatore, Digilio, Anna F., Scalabrì, Francesco, Pepe, Giuseppe, Elifani, Francesca, Madonna, Michele, Jeong, Se Kyoo, Park, Bu-Mahn, D’Esposito, Maurizio, Bowman, Aaron B., Barker, Roger A., Maglione, Vittorio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509685/
https://ncbi.nlm.nih.gov/pubmed/28706199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05709-y
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge