De novo Synthesis of Sphingolipids Is Defective in Experimental Models of Huntington's Disease

Alterations of lipid metabolism have been frequently associated with Huntington's disease (HD) over the past years. HD is the most common neurodegenerative disorder, with a complex pathogenic profile, typically characterized by progressive striatal and cortical degeneration and associated motor...

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Dades bibliogràfiques
Publicat a:Front Neurosci
Autors principals: Di Pardo, Alba, Basit, Abdul, Armirotti, Andrea, Amico, Enrico, Castaldo, Salvatore, Pepe, Giuseppe, Marracino, Federico, Buttari, Fabio, Digilio, Anna F., Maglione, Vittorio
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742211/
https://ncbi.nlm.nih.gov/pubmed/29311779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00698
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