De novo Synthesis of Sphingolipids Is Defective in Experimental Models of Huntington's Disease

Alterations of lipid metabolism have been frequently associated with Huntington's disease (HD) over the past years. HD is the most common neurodegenerative disorder, with a complex pathogenic profile, typically characterized by progressive striatal and cortical degeneration and associated motor...

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Bibliographic Details
Published in:Front Neurosci
Main Authors: Di Pardo, Alba, Basit, Abdul, Armirotti, Andrea, Amico, Enrico, Castaldo, Salvatore, Pepe, Giuseppe, Marracino, Federico, Buttari, Fabio, Digilio, Anna F., Maglione, Vittorio
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742211/
https://ncbi.nlm.nih.gov/pubmed/29311779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00698
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