Impairment of blood-brain barrier is an early event in R6/2 mouse model of Huntington Disease

Blood-brain barrier (BBB) breakdown, due to the concomitant disruption of the tight junctions (TJs), normally required for the maintenance of BBB function, and to the altered transport of molecules between blood and brain and vice-versa, has been suggested to significantly contribute to the developm...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Di Pardo, Alba, Amico, Enrico, Scalabrì, Francesco, Pepe, Giuseppe, Castaldo, Salvatore, Elifani, Francesca, Capocci, Luca, De Sanctis, Claudia, Comerci, Laura, Pompeo, Francesco, D’Esposito, Maurizio, Filosa, Stefania, Crispi, Stefania, Maglione, Vittorio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259798/
https://ncbi.nlm.nih.gov/pubmed/28117381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41316
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