Impairment of blood-brain barrier is an early event in R6/2 mouse model of Huntington Disease

Blood-brain barrier (BBB) breakdown, due to the concomitant disruption of the tight junctions (TJs), normally required for the maintenance of BBB function, and to the altered transport of molecules between blood and brain and vice-versa, has been suggested to significantly contribute to the developm...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Di Pardo, Alba, Amico, Enrico, Scalabrì, Francesco, Pepe, Giuseppe, Castaldo, Salvatore, Elifani, Francesca, Capocci, Luca, De Sanctis, Claudia, Comerci, Laura, Pompeo, Francesco, D’Esposito, Maurizio, Filosa, Stefania, Crispi, Stefania, Maglione, Vittorio
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259798/
https://ncbi.nlm.nih.gov/pubmed/28117381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41316
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