Elimination of undifferentiated human embryonic stem cells by cardiac glycosides

An important safety concern in the use of human pluripotent stem cells (hPSCs) is tumorigenic risk, because these cells can form teratomas after an in vivo injection at ectopic sites. Several thousands of undifferentiated hPSCs are sufficient to induce teratomas in a mouse model. Thus, it is critica...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lin, Yu-Tsen, Wang, Cheng-Kai, Yang, Shang-Chih, Hsu, Shu-Ching, Lin, Hsuan, Chang, Fang-Pei, Kuo, Tzu-Chien, Shen, Chia-Ning, Chiang, Po-Ming, Hsiao, Michael, Lu, Frank Leigh, Lu, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509667/
https://ncbi.nlm.nih.gov/pubmed/28706279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05616-2
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