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Efficient Generation of Chemically Induced Mesenchymal Stem Cells from Human Dermal Fibroblasts

Human mesenchymal stromal/stem cells (MSCs) are multipotent and currently undergoing hundreds of clinical trials for disease treatments. To date, no studies have generated induced MSCs from skin fibroblasts with chemicals or growth factors. Here, we established the first chemical method to convert p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lai, Pei-Lun, Lin, Hsuan, Chen, Shang-Fu, Yang, Shang-Chih, Hung, Kuo-Hsuan, Chang, Ching-Fang, Chang, Hsiang-Yi, Lu, Frank Leigh, Lee, Yi-Hsuan, Liu, Yu-Chuan, Huang, Hsiao-Chun, Lu, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356011/
https://ncbi.nlm.nih.gov/pubmed/28303927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44534
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