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ABCB1 Genotype is Associated with Fentanyl Requirements in Critically Ill Children
BACKGROUND: The gene ABCB1 encodes p-glycoprotein, a xenobiotic efflux pump capable of transporting certain opioids, including fentanyl. ABCB1 genotype has been previously associated with patient opioid requirements and may influence fentanyl dosing requirements in critically ill children. METHODS:...
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| Publicado no: | Pediatr Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5509475/ https://ncbi.nlm.nih.gov/pubmed/28388599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2017.103 |
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