Factors Contributing to Fentanyl Pharmacokinetic Variability among Diagnostically Diverse Critically-Ill Children

OBJECTIVE: To characterize the population pharmacokinetics (PK) of fentanyl and identify factors that contribute to exposure variability in critically ill pediatric patients. DESIGN: Single-center, retrospective cohort study using electronic record data and remnant blood samples. SETTING: Mixed medi...

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Udgivet i:Clin Pharmacokinet
Main Authors: Hagos, Fanuel T., Horvat, Christopher M., Au, Alicia K., Conley, Yvette, Kochanek, Patrick M., Clark, Robert S. B., Empey, Philip E.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7122686/
https://ncbi.nlm.nih.gov/pubmed/31168770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-019-00773-1
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