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Higher order oligomerization of the licensing ORC4 protein is required for polar body extrusion in murine meiosis
We have previously shown that the DNA replication licensing factor ORC4 forms a cage around the chromosomes that are extruded in both polar bodies during murine oogenesis, but not around the chromosomes that are retained in the oocyte or around the sperm chromatin. We termed this structure the ORC4...
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| Publicado en: | J Cell Biochem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5509474/ https://ncbi.nlm.nih.gov/pubmed/28230328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25949 |
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