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Spatial and temporal resolution of mORC4 fluorescent variants reveals structural requirements for achieving higher order self-association and pronuclei entry
The Origin Replication Complex (ORC), which is a multi-subunit protein complex composed of six proteins ORC1–6, is essential for initiating licensing at DNA replication origins. We have previously reported that ORC4 has an alternative function wherein it forms a cage surrounding the extruded chromat...
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| Publicado no: | Methods Appl Fluoresc |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6636821/ https://ncbi.nlm.nih.gov/pubmed/30865939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/2050-6120/ab0f57 |
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