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Higher order oligomerization of the licensing ORC4 protein is required for polar body extrusion in murine meiosis

We have previously shown that the DNA replication licensing factor ORC4 forms a cage around the chromosomes that are extruded in both polar bodies during murine oogenesis, but not around the chromosomes that are retained in the oocyte or around the sperm chromatin. We termed this structure the ORC4...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Nguyen, Hieu, James, Nicholas G., Nguyen, Lynn, Nguyen, Thien P., Vuong, Cindy, Ortega, Michael, Jameson, David M., Ward, W. Steven
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509474/
https://ncbi.nlm.nih.gov/pubmed/28230328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25949
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