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Unique Pattern of ORC2 and MCM7 Localization During DNA Replication Licensing in the Mouse Zygote
In eukaryotes, DNA synthesis is preceded by licensing of replication origins. We examined the subcellular localization of two licensing proteins, ORC2 and MCM7, in the mouse zygotes and two-cell embryos. In somatic cells ORC2 remains bound to DNA replication origins throughout the cell cycle, while...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Society for the Study of Reproduction, Inc.
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463414/ https://ncbi.nlm.nih.gov/pubmed/22674395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.101774 |
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