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Unique Pattern of ORC2 and MCM7 Localization During DNA Replication Licensing in the Mouse Zygote

In eukaryotes, DNA synthesis is preceded by licensing of replication origins. We examined the subcellular localization of two licensing proteins, ORC2 and MCM7, in the mouse zygotes and two-cell embryos. In somatic cells ORC2 remains bound to DNA replication origins throughout the cell cycle, while...

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Bibliografiset tiedot
Päätekijät: Ortega, Michael A., Marh, Joel, Alarcon, Vernadeth B., Ward, W. Steven
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for the Study of Reproduction, Inc. 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463414/
https://ncbi.nlm.nih.gov/pubmed/22674395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.101774
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