GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in βIRKO mice

AIMS/HYPOTHESIS: We aimed to investigate potential interactions between insulin and glucagon-like peptide (GLP)-1 signalling pathways in the regulation of beta cell-cycle dynamics in vivo, in the context of the therapeutic potential of GLP-1 to modulate impaired beta cell function. METHODS: Beta cel...

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Bibliografske podrobnosti
izdano v:Diabetologia
Main Authors: Kawamori, Dan, Shirakawa, Jun, Liew, Chong Wee, Hu, Jiang, Morioka, Tomoaki, Duttaroy, Alokesh, Burkey, Bryan, Kulkarni, Rohit N.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508991/
https://ncbi.nlm.nih.gov/pubmed/28526921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4303-6
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