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Insulin Signaling in α-cells Modulates Glucagon Secretion in vivo
Glucagon plays an important role in glucose homeostasis by regulating hepatic glucose output in both normo- and hypo-glycemic conditions. In this study, we created and characterized α-cell specific insulin receptor knockout (αIRKO) mice to directly explore the role of insulin signaling in the regula...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694613/ https://ncbi.nlm.nih.gov/pubmed/19356716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.02.007 |
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