Insulin Signaling in α-cells Modulates Glucagon Secretion in vivo

Glucagon plays an important role in glucose homeostasis by regulating hepatic glucose output in both normo- and hypo-glycemic conditions. In this study, we created and characterized α-cell specific insulin receptor knockout (αIRKO) mice to directly explore the role of insulin signaling in the regula...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kawamori, Dan, Kurpad, Amarnath J., Hu, Jiang, Liew, Chong Wee, Shih, Judy L., Ford, Eric L., Herrera, Pedro L., Polonsky, Kenneth S., McGuinness, Owen P., Kulkarni, Rohit N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694613/
https://ncbi.nlm.nih.gov/pubmed/19356716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.02.007
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