Intrinsic Subtype Switching and Acquired ERBB2/HER2 Amplifications and Mutations in Breast Cancer Brain Metastases

IMPORTANCE: Patients with breast cancer (BrCa) brain metastases (BrM) have limited therapeutic options. A better understanding of molecular alterations acquired in BrM could identify clinically actionable metastatic dependencies. OBJECTIVE: To determine whether there are intrinsic subtype difference...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Priedigkeit, Nolan, Hartmaier, Ryan J., Chen, Yijing, Vareslija, Damir, Basudan, Ahmed, Watters, Rebecca J., Thomas, Roby, Leone, Jose P., Lucas, Peter C., Bhargava, Rohit, Hamilton, Ronald L., Chmielecki, Juliann, Puhalla, Shannon L., Davidson, Nancy E., Oesterreich, Steffi, Brufsky, Adam M., Young, Leonie, Lee, Adrian V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508875/
https://ncbi.nlm.nih.gov/pubmed/27926948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2016.5630
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