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Influence of genetic variants on toxicity to anti-tubercular agents: a systematic review and meta-analysis (protocol)

BACKGROUND: Tuberculosis patients receiving anti-tuberculosis treatment may experience serious adverse drug reactions, such as hepatotoxicity. Genetic risk factors, such as polymorphisms of the NAT2, CYP2E1 and GSTM1 genes, may increase the risk of experiencing such toxicity events. Many pharmacogen...

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Bibliografiska uppgifter
I publikationen:Syst Rev
Huvudupphovsmän: Richardson, Marty, Kirkham, Jamie, Dwan, Kerry, Sloan, Derek, Davies, Geraint, Jorgensen, Andrea
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508765/
https://ncbi.nlm.nih.gov/pubmed/28701180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13643-017-0533-4
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