Influence of genetic variants on toxicity to anti-tubercular agents: a systematic review and meta-analysis (protocol)

BACKGROUND: Tuberculosis patients receiving anti-tuberculosis treatment may experience serious adverse drug reactions, such as hepatotoxicity. Genetic risk factors, such as polymorphisms of the NAT2, CYP2E1 and GSTM1 genes, may increase the risk of experiencing such toxicity events. Many pharmacogen...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Syst Rev
Main Authors: Richardson, Marty, Kirkham, Jamie, Dwan, Kerry, Sloan, Derek, Davies, Geraint, Jorgensen, Andrea
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Protocol
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508765/
https://ncbi.nlm.nih.gov/pubmed/28701180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13643-017-0533-4
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