Influence of genetic variants on toxicity to anti-tubercular agents: a systematic review and meta-analysis (protocol)

BACKGROUND: Tuberculosis patients receiving anti-tuberculosis treatment may experience serious adverse drug reactions, such as hepatotoxicity. Genetic risk factors, such as polymorphisms of the NAT2, CYP2E1 and GSTM1 genes, may increase the risk of experiencing such toxicity events. Many pharmacogen...

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Vydáno v:Syst Rev
Hlavní autoři: Richardson, Marty, Kirkham, Jamie, Dwan, Kerry, Sloan, Derek, Davies, Geraint, Jorgensen, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Protocol
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508765/
https://ncbi.nlm.nih.gov/pubmed/28701180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13643-017-0533-4
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