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Advances in the development of aptamer drug conjugates (ApDC) for targeted drug delivery
A key goal of modernmedicine is target-specific therapeutic intervention.However, most drugs lackselectivity, resulting in“off-target” side effects.To address the requirements of “targeted therapy,”aptamers, which are artificial oligonucleotides,have beenusedas novel targeting ligands to construct a...
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| Pubblicato in: | Wiley Interdiscip Rev Nanomed Nanobiotechnol |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5507701/ https://ncbi.nlm.nih.gov/pubmed/27800663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wnan.1438 |
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