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Advances in the development of aptamer drug conjugates (ApDC) for targeted drug delivery

A key goal of modernmedicine is target-specific therapeutic intervention.However, most drugs lackselectivity, resulting in“off-target” side effects.To address the requirements of “targeted therapy,”aptamers, which are artificial oligonucleotides,have beenusedas novel targeting ligands to construct a...

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Bibliografiske detaljer
Udgivet i:Wiley Interdiscip Rev Nanomed Nanobiotechnol
Main Authors: Chen, Ke, Liu, Bo, Yu, Bo, Zhong, Wen, Lu, Yi, Zhang, Jiani, Liao, Jie, Liu, Jun, Pu, Ying, Qiu, Liping, Zhang, Liqin, Liu, Huixia, Tan, Weihong
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507701/
https://ncbi.nlm.nih.gov/pubmed/27800663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wnan.1438
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