Automated Modular Synthesis of Aptamer–Drug Conjugates for Targeted Drug Delivery

[Image: see text] Aptamer–drug conjugates (ApDCs) are promising targeted drug delivery systems for reducing toxicity while increasing the efficacy of chemotherapy. However, current ApDC technologies suffer from problems caused by the complicated preparation and low controllability of drug–aptamer co...

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Autors principals: Wang, RuoWen, Zhu, Guizhi, Mei, Lei, Xie, Yan, Ma, Haibin, Ye, Mao, Qing, Feng-Ling, Tan, Weihong
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985443/
https://ncbi.nlm.nih.gov/pubmed/24483627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4117395
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