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Tissue plasminogen activator mediates deleterious complement cascade activation in stroke

The use of intravenous tissue plasminogen activator (tPA) in the treatment of ischemic stroke is limited by its propensity to exacerbate brain edema and hemorrhage. The mechanisms underlying these deleterious effects of tPA remain incompletely understood. The purpose of this study was to delineate a...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Zhao, Xue-Jun, Larkin, Timothy M., Lauver, Molly A., Ahmad, Saif, Ducruet, Andrew F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507253/
https://ncbi.nlm.nih.gov/pubmed/28700732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180822
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