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Structural basis of head to head polyketide fusion by CorB

Corallopyronin A is a polyketide derived from the myxobacterium Corallococcus coralloides with potent antibiotic features. The gene cluster responsible for the biosynthesis of corallopyronin A has been described recently, and it was proposed that CorB acts as a ketosynthase to interconnect two polyk...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Zocher, Georg, Vilstrup, Joachim, Heine, Daniel, Hallab, Asis, Goralski, Emilie, Hertweck, Christian, Stahl, Mark, Schäberle, Till F., Stehle, Thilo
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506619/
https://ncbi.nlm.nih.gov/pubmed/28757960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc02488a
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