Structure of the HCMV UL16-MICB Complex Elucidates Select Binding of a Viral Immunoevasin to Diverse NKG2D Ligands

The activating immunoreceptor NKG2D promotes elimination of infected or malignant cells by cytotoxic lymphocytes through engagement of stress-induced MHC class I-related ligands. The human cytomegalovirus (HCMV)-encoded immunoevasin UL16 subverts NKG2D-mediated immune responses by retaining a select...

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Bibliografiska uppgifter
Huvudupphovsmän: Müller, Steffen, Zocher, Georg, Steinle, Alexander, Stehle, Thilo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797645/
https://ncbi.nlm.nih.gov/pubmed/20090832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000723
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