Human Cytomegalovirus Glycoprotein UL16 Causes Intracellular Sequestration of NKG2D Ligands, Protecting Against Natural Killer Cell Cytotoxicity

The activating receptor, NKG2D, is expressed on a variety of immune effector cells and recognizes divergent families of major histocompatibility complex (MHC) class I–related ligands, including the MIC and ULBP proteins. Infection, stress, or transformation can induce NKG2D ligand expression, result...

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Main Authors: Dunn, Claire, Chalupny, N. Jan, Sutherland, Claire L., Dosch, Stephanie, Sivakumar, P.V., Johnson, David C., Cosman, David
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2003
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193902/
https://ncbi.nlm.nih.gov/pubmed/12782710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20022059
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