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Human Cytomegalovirus Glycoprotein UL16 Causes Intracellular Sequestration of NKG2D Ligands, Protecting Against Natural Killer Cell Cytotoxicity

The activating receptor, NKG2D, is expressed on a variety of immune effector cells and recognizes divergent families of major histocompatibility complex (MHC) class I–related ligands, including the MIC and ULBP proteins. Infection, stress, or transformation can induce NKG2D ligand expression, result...

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Detalhes bibliográficos
Main Authors: Dunn, Claire, Chalupny, N. Jan, Sutherland, Claire L., Dosch, Stephanie, Sivakumar, P.V., Johnson, David C., Cosman, David
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193902/
https://ncbi.nlm.nih.gov/pubmed/12782710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20022059
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