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Deletion of ghrelin prevents aging‐associated obesity and muscle dysfunction without affecting longevity

During aging, decreases in energy expenditure and locomotor activity lead to body weight and fat gain. Aging is also associated with decreases in muscle strength and endurance leading to functional decline. Here, we show that lifelong deletion of ghrelin prevents development of obesity associated wi...

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Dades bibliogràfiques
Publicat a:Aging Cell
Autors principals: Guillory, Bobby, Chen, Ji‐an, Patel, Shivam, Luo, Jiaohua, Splenser, Andres, Mody, Avni, Ding, Michael, Baghaie, Shiva, Anderson, Barbara, Iankova, Blaga, Halder, Tripti, Hernandez, Yamileth, Garcia, Jose M.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506439/
https://ncbi.nlm.nih.gov/pubmed/28585250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12618
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