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Deletion of ghrelin prevents aging‐associated obesity and muscle dysfunction without affecting longevity

During aging, decreases in energy expenditure and locomotor activity lead to body weight and fat gain. Aging is also associated with decreases in muscle strength and endurance leading to functional decline. Here, we show that lifelong deletion of ghrelin prevents development of obesity associated wi...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Guillory, Bobby, Chen, Ji‐an, Patel, Shivam, Luo, Jiaohua, Splenser, Andres, Mody, Avni, Ding, Michael, Baghaie, Shiva, Anderson, Barbara, Iankova, Blaga, Halder, Tripti, Hernandez, Yamileth, Garcia, Jose M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506439/
https://ncbi.nlm.nih.gov/pubmed/28585250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12618
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