Transcription factors CEP‐1/p53 and CEH‐23 collaborate with AAK‐2/AMPK to modulate longevity in Caenorhabditis elegans.

A decline in mitochondrial electron transport chain (ETC) function has long been implicated in aging and various diseases. Recently, moderate mitochondrial ETC dysfunction has been found to prolong lifespan in diverse organisms, suggesting a conserved and complex role of mitochondria in longevity de...

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Vydáno v:Aging Cell
Hlavní autoři: Chang, Hsin‐Wen, Pisano, Steve, Chaturbedi, Amaresh, Chen, Jennifer, Gordon, Sarah, Baruah, Aiswarya, Lee, Siu Sylvia
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506430/
https://ncbi.nlm.nih.gov/pubmed/28560849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12619
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