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Transcription factors CEP‐1/p53 and CEH‐23 collaborate with AAK‐2/AMPK to modulate longevity in Caenorhabditis elegans.
A decline in mitochondrial electron transport chain (ETC) function has long been implicated in aging and various diseases. Recently, moderate mitochondrial ETC dysfunction has been found to prolong lifespan in diverse organisms, suggesting a conserved and complex role of mitochondria in longevity de...
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| Publicat a: | Aging Cell |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5506430/ https://ncbi.nlm.nih.gov/pubmed/28560849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12619 |
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