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The replicative lifespan‐extending deletion of SGF73 results in altered ribosomal gene expression in yeast
Sgf73, a core component of SAGA, is the yeast orthologue of ataxin‐7, which undergoes CAG–polyglutamine repeat expansion leading to the human neurodegenerative disease spinocerebellar ataxia type 7 (SCA7). Deletion of SGF73 dramatically extends replicative lifespan (RLS) in yeast. To further define...
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| 出版年: | Aging Cell |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5506417/ https://ncbi.nlm.nih.gov/pubmed/28568901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12611 |
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