The replicative lifespan‐extending deletion of SGF73 results in altered ribosomal gene expression in yeast

Sgf73, a core component of SAGA, is the yeast orthologue of ataxin‐7, which undergoes CAG–polyglutamine repeat expansion leading to the human neurodegenerative disease spinocerebellar ataxia type 7 (SCA7). Deletion of SGF73 dramatically extends replicative lifespan (RLS) in yeast. To further define...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Aging Cell
Autors principals: Mason, Amanda G., Garza, Renee M., McCormick, Mark A., Patel, Bhumil, Kennedy, Brian K., Pillus, Lorraine, La Spada, Albert R.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506417/
https://ncbi.nlm.nih.gov/pubmed/28568901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12611
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars