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The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction
We have analyzed the yeast replicative lifespan of a large number of ORF deletions. Here we report that strains lacking genes SGF73, SGF11, and UBP8, encoding SAGA/SLIK complex histone deubiquitinase module (DUBm) components, are exceptionally long-lived. Strains lacking other SAGA/SALSA components,...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4284099/ https://ncbi.nlm.nih.gov/pubmed/25043177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.037 |
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