The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction

We have analyzed the yeast replicative lifespan of a large number of ORF deletions. Here we report that strains lacking genes SGF73, SGF11, and UBP8, encoding SAGA/SLIK complex histone deubiquitinase module (DUBm) components, are exceptionally long-lived. Strains lacking other SAGA/SALSA components,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: McCormick, Mark A., Mason, Amanda G., Guyenet, Stephan J., Dang, Weiwei, Garza, Renee M., Ting, Marc K., Moller, Rick M., Berger, Shelley L., Kaeberlein, Matt, Pillus, Lorraine, La Spada, Albert R., Kennedy, Brian K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284099/
https://ncbi.nlm.nih.gov/pubmed/25043177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.037
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