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Histone H4 lysine-16 acetylation regulates cellular lifespan
Cells undergoing developmental processes are characterized by persistent non-genetic alterations in chromatin, termed epigenetic changes, represented by distinct patterns of DNA methylation and histone post-translational modifications. Sirtuins, a group of conserved NAD(+)-dependent deacetylases or...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2702157/ https://ncbi.nlm.nih.gov/pubmed/19516333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08085 |
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