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TPX2 Impacts Acetylation of Histone H4 at Lysine 16: Implications for DNA Damage Response
During interphase, the spindle assembly factor TPX2 is compartmentalized in the nucleus where its roles remain largely uncharacterized. Recently, we found that TPX2 regulates the levels of serine 139-phosphoryated H2AX (γ-H2AX) at chromosomal breaks induced by ionizing radiation. Here, we report tha...
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| Publicado no: | PLoS One |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217740/ https://ncbi.nlm.nih.gov/pubmed/25365214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110994 |
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