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TPX2 Impacts Acetylation of Histone H4 at Lysine 16: Implications for DNA Damage Response

During interphase, the spindle assembly factor TPX2 is compartmentalized in the nucleus where its roles remain largely uncharacterized. Recently, we found that TPX2 regulates the levels of serine 139-phosphoryated H2AX (γ-H2AX) at chromosomal breaks induced by ionizing radiation. Here, we report tha...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Neumayer, Gernot, Nguyen, Minh Dang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217740/
https://ncbi.nlm.nih.gov/pubmed/25365214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110994
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