Φορτώνει......
Impairment of insulin signalling in peripheral tissue fails to extend murine lifespan
Impaired insulin/IGF1 signalling has been shown to extend lifespan in model organisms ranging from yeast to mammals. Here we sought to determine the effect of targeted disruption of the insulin receptor (IR) in non‐neuronal tissues of adult mice on the lifespan. We induced hemizygous (PerIRKO (+/−))...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Aging Cell |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5506415/ https://ncbi.nlm.nih.gov/pubmed/28544360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12610 |
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