D-Glucosamine supplementation extends life span of nematodes and of ageing mice

D-Glucosamine (GlcN) is a freely available and commonly used dietary supplement potentially promoting cartilage health in humans, which also acts as an inhibitor of glycolysis. Here we show that GlcN, independent of the hexosamine pathway, extends Caenorhabditis elegans life span by impairing glucos...

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Detalhes bibliográficos
Main Authors: Weimer, Sandra, Priebs, Josephine, Kuhlow, Doreen, Groth, Marco, Priebe, Steffen, Mansfeld, Johannes, Merry, Troy L., Dubuis, Sébastien, Laube, Beate, Pfeiffer, Andreas F., Schulz, Tim J., Guthke, Reinhard, Platzer, Matthias, Zamboni, Nicola, Zarse, Kim, Ristow, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988823/
https://ncbi.nlm.nih.gov/pubmed/24714520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4563
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