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Progressive Changes in CXCR4 Expression That Define Thymocyte Positive Selection Are Dispensable For Both Innate and Conventional αβT-cell Development

The ordered migration of immature thymocytes through thymic microenvironments generates both adaptive MHC restricted αβT-cells and innate CD1d-restricted iNKT-cells. While several chemokine receptors and ligands control multiple stages of this process, their involvement during early thymocyte develo...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Lucas, Beth, White, Andrea J., Parnell, Sonia M., Henley, Peter M., Jenkinson, William E., Anderson, Graham
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505955/
https://ncbi.nlm.nih.gov/pubmed/28698642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05182-7
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